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In cultured human aortic endothelial cells, ebselen attenuated hydrogen peroxide-mediated upregulation of pro-inflammatory pathways that are associated with atherogenesis, such as the activation of NFkB and JNK signaling and the increased expression of TNF- and NOX2 [81]

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[DOI] [PubMed] [Google Scholar] 50.Komatsubara S, Mori S, Mashiba T, Nonaka K, Seki A, Akiyama T, et al

Microbiome as a target for antidepressant chinese medicine Application of microbiomics in antidepressant Chinese medicine targets The microbiome has increasingly emerged as a key target in the study of antidepressant Chinese medicine